[ Using a mouse model in which the NF1 gene was deleted in Schwann cells, investigators from Cincinnati Children’s found that those cells were the main source of excess GDNF. The protein acted through a receptor called GFRα1 on pain-sensing nerve fibers, helping drive mechanical hypersensitivity. Credit: Cincinnati Children’s Researchers …

[ Credit: Pixabay/CC0 Public Domain University of Warwick researchers have played a central role in developing new position statements from the UK National Screening Committee (UK NSC), setting out how emerging cancer screening technologies should be evaluated before being introduced to patients. Published today in the BMJ, the statements covering …

[ Credit: Pixabay/CC0 Public Domain Chikungunya (“to become contorted” in the Kimakonde language, named after the characteristic joint ache) is classified as one of the neglected tropical diseases by the World Health Organization. It’s caused by a virus spread by Aedes mosquitoes. Symptoms include high fever, muscle and back pain, …

[ Enough time had passed since the patient’s previous colonoscopy that she met the criteria to undergo another, said Dr. Steven Itzkowitz, a gastroenterologist at the Icahn School of Medicine at Mount Sinai in New York. She was in “reasonably good health,” and the risks of the procedure — bleeding, …

[ A simulated shopping experience created for the experiment, featuring multi-colored Nutri-Score labels on the packaging and the price tags. Credit: Isabelle Weiß Anyone seeking to purchase healthy products at the supermarket needs clear guidance. Nutritional labeling schemes, such as Nutri-Score labels, are designed to help with that. The Nutri-Score …

Mental health patients say nobody listened to their concerns about a north-east England trust. BBC News

[ Credit: cottonbro studio from Pexels Children recover significantly faster from concussion after receiving early, multidisciplinary care designed to treat persistent symptoms, according to a new study. The model will provide a blueprint for future child-specific concussion clinics across Australia. The results, published in the British Journal of Sports Medicine, …

[ PAG microinjection of fluorescently labeled muscimol for visualization of injection spread using the same injection coordinates, rate, and volume as performed for the ligand microinfusions. Credit: Nature Communications (2026). DOI: 10.1038/s41467-026-73266-y Researchers have a better understanding of the nocebo effect and the neuroscience behind it all. Opposite of the …

[ Credit: Korea Advanced Institute of Science and Technology People often say that seeking psychiatric care can feel intimidating. Patients may feel burdened when they first open up about their emotional distress, while medical staff must accurately understand a patient’s extensive history and symptoms within limited consultation time. Korean researchers …

[ Researchers at University of California San Diego have developed a new artificial intelligence (AI) model that can translate a tumor’s complex genetic profile into predictions about how that cancer may respond to treatment. The model, called MutationProjector, was trained on genomic data from more than 30,000 tumors across 10 …

[ Credit: Pixabay/CC0 Public Domain Researchers have discovered how part of the body’s immune system could better combat a leading cause of death for people with cystic fibrosis (CF). A team led by The University of Queensland’s Professor Peter Sly and Dr. Abdullah Tarique has identified how macrophages—the white blood …

[ Cancer diagnosis can be challenging, and delayed diagnosis can allow cancer to progress, complicating treatment. Oral squamous cell carcinoma (OSCC), the most common type of oral cancer, can sometimes mimic benign conditions, such as gum disease or oral infections, making diagnosis difficult. Therefore, identifying new diagnostic methods for OSCC …

[ Credit: CDC/Cynthia Goldsmith A Spaniard placed under quarantine after partaking in a cruise hit by a deadly hantavirus outbreak has tested positive, the Spanish Ministry of Health said on Monday. “The patient was transferred to a high-level isolation unit in the Gomez Ulla hospital, where he will remain hospitalized,” …

[ A largely overlooked space between cells in women’s brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study. Source link

[ Respiratory syncytial virus (RSV) is a common respiratory virus that can cause severe breathing complications in babies, especially those younger than 6 months old. While many adults recover quickly from RSV with mild symptoms similar to a cold, infants often face a much greater risk of hospitalization due to …

Most cases are in the Northern Territory with some also in Western Australia, South Australia and Queensland. BBC News

[ Credit: Anna Tarazevich from Pexels Ceramides—lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death—and their metabolites have been implicated in the development of cancer and other conditions. New research indicates that different ceramide metabolism in Black and white individuals with metastatic castration-resistant prostate …

[ Women are more likely to face delays in diagnosis of cardiovascular disease and, as a result, they are more likely to die or develop more serious illness. To address this inequality, Europe needs dedicated women’s heart centers, according to a report published in the European Heart Journal. Source link

Health experts in Jersey say the change helps people realise it is not an ovaries-only condition. BBC News

[ The U.S. Food and Drug Administration has approved AstraZeneca’s Enhertu (fam-trastuzumab deruxtecan-nxki) for both the neoadjuvant and adjuvant treatment of patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. Source link