[ Cannabinoid receptor signaling in renal injury and repair: established, emerging, and unresolved mechanisms. The image summarizes the established roles of CB1 and CB2 activation in the kidney, along with their key effects on metabolism, inflammation, and cardiovascular function in the context of renal pathophysiology. Question marks indicate areas of …

[ Sedentary lifestyles are associated with approximately 5 million deaths annually. Credit: Cecília Bastos/USP Imagens A 10-year study of residents of São Paulo, Brazil, reveals that leisure-time physical activity is highly unequal and that the gap between social strata is widening. While highly educated white men are exercising more, women …

[ Traditional Chinese exercises like Tai Chi ranked best for lowering systolic blood pressure and raising good cholesterol. Credit: Pexels. Not every disease announces itself with obvious symptoms. Some develop quietly, going unnoticed until they begin to take a serious toll on health. Metabolic syndrome (MetS) is one of them. …

[ This depicts the process of providing optimized, customized medi-foods for patients or elderly individuals with dysphagia using 3D food printing technology. By precisely controlling individual nutrition, texture, and shape, the technology can help address nutritional imbalance and improve meal satisfaction and quality of life for elderly populations. Credit: Korea …

[ L1 sequence enrichment is an outcome of XCI. Credit: Science (2026). DOI: 10.1126/science.adz8081 In a study published in the journal Science, researchers in Queensland and the United States discovered that the human X chromosome attracts an unusual kind of DNA mutation, potentially doubling the risk of certain genetic disorders, …

[ Neural Dynamics Lab scientists developed “eGoT,” an algorithm that teaches AI to synthesize knowledge across domains and hallucinate less. Credit: Matthew Modoono/Northeastern University Ever notice how chatbots often insist on making up an answer instead of admitting defeat? Like a student desperately scribbling nonsense to avoid handing in a …

Dr Xand van Tulleken and Professor Sunita Sar explore why we follow advice we suspect is bad for us. BBC News

[ Credit: Brad on Unsplash Celiac disease is an autoimmune condition triggered by gluten that affects 1% to 3% of people globally and is caused by a mix of known genetic factors and unknown environmental ones. A study in Frontiers in Microbiology looked at gut bacteria in children with celiac …

[ Histological image of lung tissue from a SARS-CoV-2–infected mouse fed an arginine-restricted diet. Credit: Tavazoie lab The amino acid arginine helps keep the human body humming, most notably by synthesizing proteins that carry out a range of cellular processes. It’s produced by our bodies and found in common high-protein …

[ Credit: Sóc Năng Động from Pexels Linguistic models that analyzed the words children used when talking about stressful events were better at predicting future mental health problems than a panel of human experts. In a study published in Nature Mental Health, researchers used four natural language processing models to …

[ The largest clinical trial of long COVID care to date has found that specialist NHS long COVID services may help reduce fatigue, one of the condition’s most common and disabling symptoms. The findings, published in Nature Medicine and led by researchers and clinicians from UCL and UCLH, come from …

[ Adult childhood cancer survivors (CCS) of acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML) and non-Hodgkin lymphoma (NHL) frequently report mental distress, fatigue and executive function (EF) impairment, according to a study published online in Current Oncology. Anna R. Franzén, Ph.D., from the Norwegian University of Science and Technology …

[ Credit: Unsplash/CC0 Public Domain A “leaky gut” might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology. The researchers found that changes to the gut microbiome in mice were linked to increased intestinal permeability (leaky gut) and increased …

[ Screening for eosinophilic esophagitis (EoE) in a pediatric asthma clinic may identify more patients than previously thought, according to a study published online June 23 in The Journal of Allergy and Clinical Immunology: In Practice. Robert E. Becker, M.D., of the Medical College of Wisconsin in Milwaukee, and colleagues …

[ Patients with deficient DNA mismatch repair (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal cancer experienced a 58% reduction in the risk of disease progression or death when treated with atezolizumab (Tecentriq) plus modified FOLFOX6 and bevacizumab (Avastin), compared with atezolizumab alone, according to results from the NRG-GI004/SWOG S1610 COMMIT …

[ Credit: Towfiqu barbhuiya from Pexels A new position paper from researchers at the University of Aberdeen warns that opioid use disorder in the U.K. is a “large and probably underestimated” problem, and that without urgent action, opioid addiction and opioid-related deaths will continue to rise. The authors argue that …

[ The U.S. Food and Drug Administration has approved Simtriyo (centanafadine) for the treatment of attention-deficit/hyperactivity disorder (ADHD) in adults and children 6 years and older weighing ≥20 kg. The once-daily extended-release capsule is the first and only approved norepinephrine, dopamine and serotonin reuptake inhibitor. The approval is based on …

[ Credit: Unsplash/CC0 Public Domain People living on the coast in midlife are more likely to have worse health, a new study of England and Wales led by UCL researchers finds. The research, published in BMJ Public Health, found that migration trends have left more disadvantaged people living in coastal …

[ Rapid repair of gut epithelial barrier structure and function (shown in yellow) driven by microbial metabolite 10-HSA. Credit: UC Davis Scientists at the UC Davis School of Medicine have identified a naturally occurring metabolite that repairs gut damage caused by HIV infection and significantly improves the effectiveness of antiretroviral …

[ The figure shows how the heart changes after a major heart attack and how the new treatment using exosomes from mesenchymal stromal cells (MSC-EVs) can slow the progression of the disease. Credit: Grinnemo et al. with images from BioArt. Many people who survive a heart attack will later develop …