[ For patients with chronic kidney disease (CKD), cognitive impairment (CI) is associated with worse outcomes, according to a study published in the May issue of Kidney International Reports. Hélène Levassort, M.D., from the Assistance Publique—Hôpitaux de Paris, and colleagues examined the specific impact of CI on adverse outcomes in …
Read More »Machine learning predicts asthma risk in children with early-life atopic dermatitis
[ Machine learning models can predict the risk for developing moderate-to-severe persistent asthma and allergic rhinitis in children diagnosed with early-life atopic dermatitis, according to a study published online April 17 in the Journal of Allergy and Clinical Immunology. Source link
Read More »Global survey reveals significant burden and inconsistent management of rare metabolic bone disorder in adults
[ Specialties involved in the management of HO disorders (N = 1058). ADHR autosomal dominant hypophosphataemia rickets, ARHR autosomal recessive hypophosphataemic rickets, CSHS cutaneous skeletal hypophosphataemia syndrome, FD fibrous dysplasia, GP general practitioner, HO hypophosphataemic osteomalacia, MAS McCune–Albright syndrome, TIO tumour-induced osteomalacia, XLH X-linked hypophosphataemia. Credit: Archives of Osteoporosis (2026). DOI: 10.1007/s11657-026-01692-y …
Read More »Behavioral therapy + transcutaneous tibial nerve stimulation best for overactive bladder
[ For older women, behavioral therapy (BT) reduces overactive bladder (OAB) symptoms, with greater improvements seen in combination with transcutaneous tibial nerve stimulation (TTNS), according to a study published online April 6 in PLOS ONE. Marianna Vale D’Alessandro Barbosa, from the Universidade de Brasilia in Brazil, and colleagues examined the …
Read More »Next-generation KRAS G12C inhibitor elisrasib elicited promising response rates in patients with advanced lung cancer
[ Credit: Unsplash/CC0 Public Domain Treatment with the investigational next-generation KRAS-G12C inhibitor elisrasib led to clinical benefit in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors harbored a KRAS G12C mutation and whose disease progressed after prior therapies, according to results presented at the American …
Read More »Fracture risk assessment becomes more accurate with age-based thresholds
[ Credit: Unsplash/CC0 Public Domain Fracture risk in Sweden has been overestimated, according to research from the University of Gothenburg. As health care tools are updated with new data, more people—including younger patients—may receive treatment. A widely used tool, FRAX, estimates the 10-year risk of osteoporotic fractures. The Swedish model …
Read More »HIV disrupts lung ‘clock,’ raising COPD and emphysema risk
[ FIU Medicine researcher Hoshang Unwalla and his lab led a new study that reveals how HIV causes emphysema and COPD. Credit: Florida International University People living with HIV face a greater risk of developing lung diseases at a much younger age, even if they have never smoked. FIU researchers …
Read More »After assault, OCD risk rises fastest in first year, pointing to a critical care window
[ Credit: CC0 Public Domain Obsessive compulsive disorder (OCD) is a mental health condition characterized by recurring intrusive thoughts (i.e., obsessions) and repetitive behaviors (i.e., compulsions) aimed at reducing anxiety. This disorder is estimated to affect 1.2% to 2.3% of people every year. While several past studies have investigated the …
Read More »Microplastics in human liver could be fueling global surge in disease
[ There is considerable evidence that microplastics and nanoplastics are present in the livers of humans, and wild animal populations on land and in the ocean. Now experts in environmental and human health are investigating whether the presence of these tiny plastic particles in the liver is driving disease and …
Read More »Hidden in hair follicles, immune ‘sentinel’ cells may help skin detect microbes
[ Credit: Henry Ry from Pexels Researchers at the School of Medicine at the University of California, Riverside have discovered previously unrecognized immune surveillance structures in the skin. Found within hair follicles, the cells resemble M (microfold) cells—specialized epithelial cells traditionally associated with the gut and airway tissues. The findings, …
Read More »How a chemical reaction triggers brain inflammation in Alzheimer’s disease
[ Connections between nerve cells in the brain (synapses, labeled green) usually deteriorate in the brains of Alzheimer’s mouse models (left). Stopping the formation of a molecule known as SNO-STING protects these connections between cells (right). Credit: Scripps Research. The brain has its own immune system, which detects threats and …
Read More »How different countries decide who gets a heart transplant
[ Credit: Unsplash/CC0 Public Domain As demand for heart transplants continues to far exceed the number of available donor hearts, experts at the 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) explored a critical question: how should this scarce, life-saving resource be …
Read More »Space-grown heart tissue could uncover failure pathways and improve cardiac repair
[ Credit: CC0 Public Domain By studying and engineering heart tissue in the unique low-gravity environment of space, the laboratory of Arun Sharma, Ph.D., is uncovering new ways to protect and repair the failing heart. He addressed the 46th Annual Meeting and Scientific Sessions of the International Society for Heart …
Read More »New study finds high rates of outpatient antibiotic exposure in children with medical complexity
[ Credit: CC0 Public Domain A new study from Boston Children’s Hospital found that annual prescription rates increased nonlinearly as children’s underlying level of medical complexity increased. Frequent antibiotic use has associated risks, including an increased likelihood of antibiotic-related complications (e.g., C. difficile), as well as the development of antibiotic …
Read More »Exposure to fathers' depression in pre-adolescence associated with poor educational outcomes among males
[ Preliminary findings from a national birth cohort suggest strong associations between exposure to fathers’ depression in pre-adolescence and poor educational outcomes among males, but not females. The findings suggest a strong need to identify and support fathers with depressive symptoms and their sons to promote positive educational attainment. The …
Read More »'I used delivery apps to hide the shame of alcoholism'
Hattie Underwood is a recovered alcoholic and she told 5 Live’s Naga Munchetty how she used delivery apps to “anonymise” her alcohol consumption. BBC News
Read More »Rethinking newborn screening for critical congenital heart disease
[ Critical congenital heart diseases, or CCHDs, are a group of life-threatening structural heart defects present at birth. According to the Centers for Disease Control and Prevention, about one in four babies born with a heart defect has a CCHD, and treatment—medication and/or surgery—must take place within the first year …
Read More »A blueprint for holistic cardiovascular implantable electronic device lead management and lifelong patient safety
[ The right ventricular lead positioning relative to the tricuspid valve. (A) Placement of leads on the right ventricular septum (versus apical pacing) has not been associated with worsening tricuspid regurgitation. (B) When implanting leads for left bundle branch area pacing, a shorter lead to tricuspid annulus distance can result …
Read More »New study finds states with stronger firearm laws have lower rates of youth-perpetrated firearm homicide
[ Firearm violence is the leading cause of death among U.S. youth. A new study from Boston Children’s Hospital found that youth-perpetrated firearm homicides increased by 41% between 2018 and 2022. Stronger firearm laws were associated with lower homicide rates, with states in the strongest law quintile having a 66% …
Read More »Whole-body ultrasound captures full cross-sections in 10 seconds, early tests show
[ Ultrasounds are a critical part of modern health care, helping to image soft tissue and organs, measure blood flow, and monitor fetal development. But the technique has constraints, including a limited field of view and the potential for operator error. To address current shortfalls and push the technology toward …
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