Genetically engineered CAR T cells expressing artificial receptor proteins are increasingly used in the clinic to boost the immune system’s response against leukemias and other cancers. In a study published in the Journal of Experimental Medicine (JEM), researchers in Switzerland have adapted this approach to suppress the immune system’s response to a common allergen, reducing or preventing asthma symptoms in mice. The technique could eventually be used to treat a wide variety of allergies in humans.
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