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Personalized fMRI models decode moment-to-moment chronic pain in fibromyalgia

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Chronic pain affects nearly one in five adults worldwide and remains one of the leading causes of disability. Unlike acute pain triggered by injury, chronic pain often arises spontaneously—without an obvious external cause—and fluctuates across minutes, hours, and days. Yet clinicians still rely largely on self-reported pain ratings, as there is currently no objective biomarker comparable to blood pressure or body temperature.


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