A Home Office post-mortem examination carried out on Monday confirmed the man died following a single stab wound to the chest.
Police have urged anyone with information about the stabbing to contact them.
Det Insp Dave McCormack said: “This is a complex investigation, and we are working our way methodically through the evidence.
“The man’s body was in the flat for approximately eight days before police were alerted so we need to follow several lines of inquiry.”
He said detectives believed the incident to be drug-related but did not believe it was linked to a fatal stabbing in the city’s Paragon Place in August.
“Police would like to speak to anyone who may have witnessed anything suspicious or has information about the incident,” he added.
No arrests have been made.
A police cordon remains in place, house-to-house inquiries will continue and CCTV footage will be reviewed.
The force said it was working with counterparts in the Metropolitan Police.
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