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Outlining the future of theranostics in neurooncology

Example of interventional approaches to bypass physiologic blood-brain barrier (BBB) and blood-tumor barrier (BTB). Normal transport in BBB is not included. (Left) Local delivery with administration of radioactivity directly into resection cavity. (Middle) CED: microcatheter is implanted into tumor, and hydraulic pressure is used to distribute drugs in brain parenchyma. …

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