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HPV-positive cancers hide from the immune system, but blocking a single protein could make the tumors treatable

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A team of scientists at Henry Ford Health + Michigan State University Health Sciences have uncovered a mechanism that allows certain head and neck cancers to hide from the immune system, a discovery that could change how some of the most treatment-resistant tumors are approached. The study, published in Proceedings of the National Academy of Sciences, identifies a single protein at the heart of this invisibility and shows that removing it can make hidden tumors vulnerable to treatment.


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