In 2004, Dr Jack joined the consultant medical staff at the Royal Victoria Hospital as a geriatrician.
She has worked her way through the ranks from deputy medical director to medical director and deputy chief executive before taking up the chief executive role.
Belfast Trust said she “embodies health service values and has worked diligently to ensure our patients and service users have received the best possible care”.
It wished to pay tribute to Dr Jack for “her unwavering commitment to Belfast Trust and her wider contribution to health and social care in Northern Ireland”.
Ciaran Mulgrew, Belfast Trust chair, said: “On behalf of Trust Board I want to thank Cathy for her dedication and leadership to the people we serve, and she leaves with our sincere thanks and best wishes.”
Belfast Trust will now begin the process of recruiting a new chief executive.
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