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Study maps complex interplay between cells, metabolism, and immunity in breast cancer lymph node metastasis

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A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast cancer. The findings from the study in The American Journal of Pathology, offer novel insights into the characteristics of the metastatic tumor microenvironment, providing a foundation for targeted therapeutic strategies.


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