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[ The R33Q mutation in calsequestrin 2 (CASQ2) disrupts calcium control in heart cells and activates protein-degradation mechanisms. Credit: CNIC An international team has identified a protein-degradation mechanism that contributes to the development of an inherited form of catecholaminergic polymorphic ventricular tachycardia (CPVT), a disease that mainly affects children and …

Police in South Africa say that they have found a woman’s body in a Johannesburg suburb, the tenth in recent months. The body was found on Saturday morning and identified by the friend with whom she had been at a bar the previous evening. The local police commissioner said his …

A new scheme will support first-time home buyers who can’t rely on the “bank of mum and dad”, Andy Burnham has announced. The Your First Home scheme will be targeted at those who most need support getting on to the property ladder, the government said. The prime minister said he …