Other highlights on the night will include Doctor Who star Ncuti Gatwa introducing a preview from the forthcoming Doctor Who Christmas Special.
Doctor Who fans will have the chance to own pieces of memorabilia from the show when two items go up for auction.
There will also be a performance by singer Ella Henderson, while fellow pop star Kylie Minogue has recorded a special message which will be played on the night.
Viewers can also expect a visit from the stars of Gladiators, as well as a special performance from Strictly Come Dancing as the professionals are joined by TV character Bluey.
And actor Gary Oldman will read a CBeebies bedtime story, which will be aired as part of the show.
BBC Children in Need will air at 19:00 on Friday 15 November on BBC One and BBC iPlayer.
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