Allergy affects more than one billion people worldwide—and the number is rising. For many, it means mild symptoms such as itching and a runny nose. For others, it can develop into life-threatening reactions. Now, two new studies bring researchers an important step closer to both understanding and potentially controlling the mechanisms that drive allergic disease. An international research team has mapped how the body’s central allergy antibody, IgE, functions at the molecular level—and at the same time demonstrated a new way to block allergic reactions.
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