Gus McCarthy will make his first start for Leinster in their opening United Rugby Championship game against Edinburgh at the Hive Stadium on Friday night.
The former Ireland Under-20 captain is named in the front row with Michael Milne and Thomas Clarkson.
Leo Cullen has opted for a mix of youth and experience with fellow academy graduates Charlie Tector and Conor O’Tighearnaigh also starting.
Tector partners Garry Ringrose at centre, as Jamison Gibson-Park returns from a hamstring injury, which ruled him out of Ireland’s Test games against South Africa.
Jack Conan captains the side at number eight, with Max Deegan and Scott Penny also starting in an unchanged back row from the 54-26 pre-season win over Northampton Saints two weeks ago.
New signing Rabah Slimani, who arrived from Clermont is on the bench, while double World Cup winner RG Snyman is not in the squad.
Cian Healy will equal Devin Toner’s club appearance record if he comes off the bench to play his 280th Leinster game.
Irish internationals Caelan Doris and James Lowe are missing, while Dan Sheehan is out with a knee injury.
Leinster: Jamie Osborne, Tommy O’Brien. Garry Ringrose, Charlie Tector, Jordan Larmour, Sam Prendergast, Jamison Gibson-Park, Michael Milne, Gus McCarthy, Thomas Clarkson, Conor O’Tighearnaigh, James Ryan, Max Deegan, Scott Penny, Jack Conan [captain].
Replacements: John McKee, Cian Healy, Rabah Slimani, Brian Deeny, James Culhane, Luke McGrath, Ross Byrne, Rob Russell.
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