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Engineered CAR-NK cells appear more 'attack-ready'

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Researchers at the Ribeirao Preto Blood Center and the Center for Cell-Based Therapy (CTC) conducted a study using the NK-92 cell line to test new models of chimeric antigen receptors (CARs) with specific costimulatory domains, such as 2B4 and DAP12. The tests showed that these components helped make the cells “ready to attack,” thereby increasing their ability to destroy tumors. The results were published in the journal Frontiers in Immunology.


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