Effect of GV1001 on aging, telomere maintenance, and long-term memory confirmed via bioinformatics analysis. Credit: Aging (2024). DOI: 10.18632/aging.205489 A new research paper titled “GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects” has been published in Aging. GV1001, which mimics the activity of human telomerase …

Dispartities in HIV testing for people with intellectual disabilities is becoming a common challenge. Credit: T.G. James, Department of Family Medicine, University of Michigan, Ann Arbor, MI, U.S. People with disabilities are often at higher risk for exposure to HIV due to barriers in engaging health care and other systemic …

Assessment of 3067 women augmented with oxytocin. Credit: BMJ (2023). DOI: 10.1136/bmj-2023-076515 There are approximately 130 million births per year. A substantial proportion of the women giving birth are treated with oxytocin or undergo cesarean sections. But not all the women receiving treatment actually need it, and overtreatment can be …

Example of interventional approaches to bypass physiologic blood-brain barrier (BBB) and blood-tumor barrier (BTB). Normal transport in BBB is not included. (Left) Local delivery with administration of radioactivity directly into resection cavity. (Middle) CED: microcatheter is implanted into tumor, and hydraulic pressure is used to distribute drugs in brain parenchyma. …

Simple slopes and region of significance of the interaction between age 3 exuberant temperament and directive parenting predicting age 4 executive functioning. Credit: Research on Child and Adolescent Psychopathology (2023). DOI: 10.1007/s10802-023-01140-2 Parents of young children with an excitable or exuberant temperament could adapt their parenting style to help moderate …

Habenular astrocyte acidification in the anxiogenic environment. (A) The fluorescence sensor protein E2GFP is sensitive to changes in intracellular pH. The green emission in response to purple light excitation does not change much with pH changes; however, the orange emission is largely decreased with pH acidification. E2GFP was selectively expressed …

Health officials in Hawaii have confirmed five cases of whooping cough among members of a family, including a case that has led to the hospitalization of a child.  The Hawaii Department of Health says each case of pertussis affected an unvaccinated individual and that it is working with the Centers …

Credit: AI-generated image Many people have compared the addictive nature of social media to cigarettes. Checking your likes, they say, is the new smoke break. Others say the unease over social media is just the next round of moral panic about new technologies. We are a pair of researchers who …

Credit: Pixabay/CC0 Public Domain An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London. The findings have been published in JAMA …

Credit: CC0 Public Domain In the battle to control health care costs, hospitals are deploying their political power to protect their bottom lines. The point of contention: For decades, Medicare has paid hospitals—including hospital-owned physician practices that may not be physically located in a hospital building—about double the rates it …

Credit: cottonbro studio from Pexels Women with HIV experience accelerated DNA aging, a phenomenon that can lead to poor physical function, according to a study led by Stephanie Shiau, an assistant professor in the Department of Biostatistics and Epidemiology at the Rutgers School of Public Health. Published in The Journal …

Increased fibroblast synthetic activity as early as 1 week post-filler injection. Following injection of vehicle (saline) and filler (cross-linked hyaluronic acid, CL-HA) into photodamaged skin of individuals over 60 years-old, skin samples were obtained in a paired manner at 1, 2, 3 and 4 weeks. Credit: Experimental Dermatology (2024). DOI: 10.1111/exd.14998 Chronic exposure …

Is the COVID quarantine on its way out? Amid reports that the U.S. Centers for Disease Control and Prevention (CDC) may be considering a change to its COVID isolation guidelines, doctors are sharing their own recommendations. The current CDC guidance, which was implemented in late 2021, calls for people who …

Credit: Pixabay/CC0 Public Domain A consortium of University of Birmingham researchers, clinicians and industry partners is developing a novel device that could revolutionize the clinical management of anal fistula. In this intrusive and embarrassing condition, sufferers experience daily discomfort and smelly discharge from a tunnel between the bowel and skin …

A push for more accessible HPV testing is underway. A new program called SHIP Trial Network, led by the National Cancer Institute (NCI), is exploring testing for human papillomavirus (HPV) via self-collection to prevent cervical cancer, according to a press release. The Last Mile Initiative, announced at the White House …

Co-localization of MRI Images and joint tissue obtained at surgery. Representative images of Axial and Coronal views of target knee for co-localization of knee biopsy tissue by MRI identification before tissue harvest at joint replacement surgery. MRI scans are shown alongside a macroscopic image of tibia for each subject harvested …

Credit: Unsplash/CC0 Public Domain People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study from Uppsala University confirms previous research on whether herpes can be a possible risk factor …

Flow chart describing the overall number of positive BCs, monomicrobial vs polymicrobial BCs and off-panel vs in-panel BCID detection profiles. *One or more microbes not detected. Credit: APMIS (2024). DOI: 10.1111/apm.13374 Every year some 49 million cases of sepsis occur, and 11 million sepsis-related deaths occurred worldwide in 2017, according …

A USP1 inhibitor, ML323, activates cdc42 and inhibits Ewing sarcoma growth. Credit: Genes & Cancer (2024). DOI: 10.18632/genesandcancer.235 A new research paper titled “Roles of USP1 in Ewing sarcoma” has been published in Genes & Cancer. Ewing sarcoma is a cancer of bone and soft tissue in children and young …

Credit: Pixabay/CC0 Public Domain Mothers are less likely to take antidepressants if their own parents and parents-in-law are healthy and live close by, a new study finds. On the flip side of the coin, antidepressant use was highest in mothers whose parents and parents-in-law were elderly, in poor health, and …