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Bacterial-like vaccine cues could help extend immunity against evolving viruses

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Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer-lasting vaccines for respiratory viruses like influenza and the coronavirus that causes COVID-19. The work, published March 25 in the journal Cell Reports, focuses on T cells, a type of immune cell that helps control infections by killing virus-infected cells. Unlike antibodies—the basis of most current vaccines, which can lose effectiveness as viruses mutate—T cells recognize more stable parts of viruses, offering a path to broader protection.


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