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Tag Archives: Studies

Metformin shown to prevent long COVID across risk groups in multiple randomized trials

[ Credit: CC0 Public Domain Multiple randomized clinical trials and electronic health record studies now show that metformin, a widely used and well-established medication, significantly reduces the risk of developing long COVID when taken during or shortly after acute infection with SARS-CoV-2. The findings are published in Clinical Infectious Diseases. …

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Exploring why adapting to the environment is more difficult as people age

[ Of all the brain structures related to behavioral adaptability, this collection of structures correlated with functional performance in older—but not younger—adults. Thus, age-related changes in behavioral adaptability may be reflected in the integrity of these structures. Colors indicate the associated cognitive function. AF, arcuate fasciculus; UF, uncinate fasciculus; CTh, …

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Physician group releases guideline on biologic management in severe asthma

[ Credit: Pixabay/CC0 Public Domain The American College of Chest Physicians recently released a new clinical guideline on biologic management in severe asthma. Published in the journal CHEST, the guideline contains seven evidence-based recommendations to provide a framework for pulmonologists, allergists, and immunologists to implement in their own practice. Severe …

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Deep learning creates virtual multiplexed immunostaining to improve cancer diagnosis

[ Deep learning-enabled virtual multiplexed immunostaining of label-free tissue for vascular invasion assessment. Credit: UCLA Engineering Institute for Technology Advancement Researchers at the University of California, Los Angeles (UCLA), in collaboration with pathologists from Hadassah Hebrew University Medical Center and the University of Southern California, have developed a deep learning–based …

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Expert guidance urges caution before surgery for patients with treatment-resistant constipation

[ A new update from the American Gastroenterological Association is calling for greater caution before surgery is considered for patients with refractory constipation, a severe, chronic form of constipation that does not respond to standard treatments. Credit: Clinical Gastroenterology and Hepatology A new update from the American Gastroenterological Association (AGA) …

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Study of uterine inflammation in livestock could help treat infertility in humans

[ Innate immune sensing and response pathways by endometrial epithelial and stromal cells following E. coli challenge and confirmed in animal models. Credit: Nature Reviews Immunology (2025). DOI: 10.1038/s41577-025-01200-2 Research to help reduce inflammation in the uterus of livestock animals could help pave the way for developing new drugs to …

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How pregnancy and breastfeeding enhance local immunity that cancer-proof the breast

[ For centuries, physicians observed that nuns, who are celibate, had much higher rates of breast cancer, leading to the theory that pregnancy, childbirth, and breastfeeding might be associated with lower breast cancer risk. Numerous epidemiological studies have since supported this, finding that women with more children and breastfed tend …

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Blocking a key inflammatory pathway improves liver structure and vascular function in cirrhosis, study finds

[ Antagonizing epigenetically controlled PAF/PAF-R pathway improves liver function during experimental cirrhosis. Credit: Universidad Miguel Hernández de Elche Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis. The study, published in Biomedicine …

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