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Canada must protect youth from sports betting advertising, say specialists

[ Credit: Stefan Coders from Pexels Canada must enact strong, effective legislation to protect youth from gambling advertising. Minors are suffering harms from problem gambling despite age restrictions, argue authors in an editorial in CMAJ (Canadian Medical Association Journal). Since 2021, ads for sports betting have saturated sports broadcasts, constantly …

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First-in-human trial shows promising results for antibody-drug conjugate in relapsed small cell lung cancer

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[ Credit: Pixabay/CC0 Public Domain A first-in-human Phase I study of SHR-4849 (IDE849), a Delta-like ligand 3 (DLL3)-directed antibody-drug conjugate (ADC), demonstrated manageable safety and early signs of anti-tumor activity in patients with relapsed small cell lung cancer (SCLC). The results were presented at the International Association for the Study …

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Ifinatamab deruxtecan demonstrates high response rate in previously treated extensive-stage small cell lung cancer

[ Credit: Unsplash/CC0 Public Domain Patients diagnosed with recurrent or progressive extensive-stage small cell lung cancer (ES-SCLC) may benefit from treatment with ifinatamab deruxtecan (I-DXd), a B7-H3–directed antibody–drug conjugate, according to data presented at the International Association for the Study of Lung Cancer (IASLC) 2025 World Conference on Lung Cancer …

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