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Cell-free DNA offers early warning for bloodstream infections in kids with leukemia

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Researchers have identified a promising way to predict bloodstream infections in children with high-risk leukemia days before the infection would be diagnosed using current standards of care. The test, named plasma microbial cell-free DNA sequencing (mcfDNA-Seq), detected infection-causing pathogens days before standard blood cultures, offering a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick. The study is published in The Lancet Microbe.


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