Ageing: ‘Supermodel granny’ drug extends life in animal tests

The big unanswered questions are could the same effect be achieved in people, and whether any side effects would be tolerable.

Interleukin-11 does have a role in the human body during early development.

People are, very rarely, born unable to make it. This alters how the bones in their skull fuse together, affects their joints, which can need surgery to correct, and how their teeth emerge. It also has a role in scarring.

The researchers think that later in life, interleukin-11 is playing the bad role of driving ageing.

The drug, a manufactured antibody that attacks interleukin-11, is being trialled in patients with lung fibrosis. This is where the lungs become scarred, making it harder to breathe.

Prof Cook said the trials had not been completed, however, the data suggested the drug was safe to take.

This is just the latest approach to “treating” ageing with drugs. The type-2 diabetes drug metformin and rapamycin, which is taken to prevent an organ transplant being rejected, are both actively being researched for their anti-ageing qualities.

Prof Cook thinks a drug is likely to be easier for people than calorie restriction.

“Would you want to live from the age of 40, half-starved, have a completely unpleasant life, if you’re going to live another five years at the end? I wouldn’t,” he said.