Wales will be without Aaron Ramsey, David Brooks, Tyler Roberts and Ashley Williams for next week’s Nations League double-header.
Juventus midfielder Ramsey, Bournemouth winger David Brooks and Leeds striker Tyler Roberts are injured, while defender Ashley Williams has withdrawn.
Ryan Giggs’ side face Finland in Helsinki on Thursday, 3 September and then host Bulgaria three days later.
Ben Woodburn and Brennan Johnson are called up from the Under-21s.
But Real Madrid’s Gareth Bale has reported for duty as the Wales squad enter a Covid-19 bubble ahead of their Nations League games.
Meanwhile, Finland centre-back Paulus Arajuuri has pulled out of the squad to face Wales next week through injury.