Higher live birth rates found after transferring fresh rather than frozen embryos

For women hoping to achieve a pregnancy using freshly retrieved donor eggs, a new retrospective study led by researchers from Brigham and Women’s Hospital may provide important insight. Brigham senior author Janis H. Fox, MD, had observed that when freshly retrieved donor eggs were used, pregnancy rates were higher for fresh compared to frozen embryo transfers. Fox and her colleagues were intrigued by this observation. The team set out to scientifically determine if this observation would be replicated in a larger sample of recipients. Leveraging national data from the Society for Assisted Reproductive Technology (SART), the Brigham researchers found that, in cycles using freshly retrieved donor eggs, fresh embryo transfers were indeed associated with significantly higher live birth rates compared to frozen embryo transfers. The team’s findings are published in JAMA.



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